Index: Karolinska Institutet: KI North: Department of Women's and Children's Health


Understanding and preventing damage to the growing skeleton caused by radiotherapy


Supervisor: Phillip Newton
Department: Women´s and Children´s Health
Postal Address: J9.30 BioClinicum building,
Visionsgatan 4,
17164
Solna

E-mail: phillip.newton@ki.se
Homepage: https://ki.se/en/kbh/skeletal-development


Radiotherapy is an important part of childhood cancer therapy. However, whilst highly effective, radiotherapy can cause severe side-effects on the growing skeleton. These skeletal malformations, such as irregular body proportions and spinal curvature, persist in childhood cancer survivors throughout their adult lives. Using conditional knockout mouse models combined with in vivo radiation protocols, our lab aims to better understand and prevent these so-called skeletal-late effects. We offer a creative and inspiring environment and are looking for friendly, enthusiastic and ambitious students to participate in this project.

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